Metabolic and Functional Consequences of Aging

This observational study aims to understand how aging affects your body's metabolism, especially how proteins and amino acids are used. Researchers will use a method called "stable tracer infusion in a postabsorptive state" where you receive special tracers (like labels) to track how your body processes amino acids, fats, and other substances. The goal is to identify metabolic patterns linked to age-related issues like reduced physical ability or thinking skills. They will measure changes in your whole-body protein and amino acid metabolism over 2 hours. This study is looking for 100 participants, aged 50 and older, who are in good health, have a stable weight, and can walk and lie down comfortably. The current recruitment status is unclear.

Study design: This is an observational study with a planned enrollment of 100 participants, aged 50 and older. It is not a drug trial but rather observes natural processes.
What's involved: You would need to be able to lie in a supine (on your back) or elevated position for up to 3 hours. You would also need to comply with study procedures, which include receiving stable tracer infusions.
Compensation: Not stated in the trial record.
Follow-up: The primary endpoint, age-related changes in whole-body protein and amino acid metabolism, is measured at 2 hours. Further follow-up is not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

Metabolic and Functional Consequences of Aging in Health and Disease

Recruiting

Not specifiedAll Ages

Updated 2026-08-26T02:18:42.501841+00:00 on ClinicalTrials.gov

Conditions

Aging

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Stable body-weight (± 5%) for the past 3 months

Subject is judged to be in satisfactory health based on medical history, physical examination, and laboratory screening evaluations.

Ability to walk, sit down and stand up independently or with walking mobility aids

Ability to lie in a supine or elevated position for up to 3 hours

Willingness and ability to comply with the protocol

Exclusion

Insulin dependent diabetes mellitus

Established diagnosis of malignancy

History of untreated metabolic diseases including hepatic or renal disorder

Presence of acute illness or metabolically unstable chronic illness

Presence of fever within the last 3 days

Use of short course of oral corticosteroids within 4 weeks preceding study day

Failure to give informed consent or Investigator's uncertainty about the willingness or ability of the subject to comply with the protocol requirements

(Possible) pregnancy

Already enrolled in another clinical trial and that clinical trial interferes with participating in this study

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