This observational study aims to understand how the lymphatic system (a network of vessels that helps drain fluid and fight infection) in the arm works, specifically looking at an "alternate pathway" called the Mascagni-Sappey (M-S) pathway. Researchers will use imaging techniques like ICG lymphography (a test using a special dye to visualize lymph vessels) and lymphoscintigraphy with SPECT/CT (another imaging method to track lymphatic flow) to map this pathway. They are studying women who have had breast cancer treatment, including lymph node removal, but did not develop lymphedema (swelling caused by lymphatic system blockage). The goal is to see if variations in this pathway can explain why some women don't get lymphedema after breast cancer treatment. This study is currently unclear on its recruitment status and does not involve any specific interventions or drugs.

Study design

This is an observational study planning to enroll 142 women. It is not a randomized or blinded study.

What's involved

Participants will have imaging tests, including ICG lymphography and lymphoscintigraphy, during one study visit. These tests involve injections and imaging at different time points.

Compensation

Not stated in the trial record.

Follow-up

Lymphatic pathway anatomy will be measured immediately, 30 minutes, and 2 hours after injections during the single study visit.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.