ACCLAIM Study: Microwave Ablation for Colorectal Liver Metastases
This study, called ACCLAIM, is looking at how well microwave ablation (MWA) works for treating colorectal liver metastases (cancer that has spread from the colon or rectum to the liver). MWA uses heat to destroy cancer cells. Researchers want to see if MWA can prevent the cancer from growing back in the treated area for at least two years. You might be able to join if you are at least 18 years old, have been diagnosed with colorectal cancer that has spread to your liver, and have up to three liver tumors, each no larger than 2.5 centimeters. The study aims to enroll about 275 people.
- Study design
- This is a multi-center study that plans to enroll about 275 participants. It is a standard of care study, meaning the treatment is already a recognized option.
- What's involved
- You would undergo microwave ablation, and your tumor margins will be assessed immediately after and again 4-8 weeks later. Imaging will be performed at 24 months to check for local tumor progression.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for at least 24 months to assess local tumor progression.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Ablation With Confirmation of Colorectal Liver Metastases (ACCLAIM)
At a glance
Conditions
Where it's being run
7 sites across 7 statesStudy leadership
- Constantinos Sofocleous, MD, PhD, FSIR, FCIRSE · PRINCIPAL_INVESTIGATOR · Memorial Sloan Kettering Cancer Center
Who to contact
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What this trial measures
- Local tumor progression free survival at 24 months24 Months
See Above