Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
This study is looking at new ways to help people with schizophrenia spectrum disorders stop smoking. It tests two types of repetitive transcranial magnetic stimulation (rTMS) devices: the active F8-coil and the active H-coil. rTMS uses magnetic fields to stimulate specific areas of the brain. Researchers believe that smoking addiction in people with schizophrenia might be linked to certain brain circuits that are also affected by schizophrenia. The study will measure how much participants smoke and look at changes in their brain's functional connectivity (how different brain areas communicate) after one month. You may be able to join if you are 22-65 years old, smoke at least 5 cigarettes a day, and have a schizophrenia-spectrum disorder. The study is currently unclear on its recruitment status and plans to enroll 50 participants.
- Study design
- This is an interventional study planning to enroll 50 participants. It compares two different rTMS devices for smoking cessation.
- What's involved
- Participants will receive multiple rTMS treatments over several days. Smoking habits and brain activity will be assessed at the beginning, during treatment, and at follow-up.
- Compensation
- Not stated in the trial record.
- Follow-up
- Smoking and brain changes will be measured at 1 month after the intervention.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Xiaoming Du, PhD · PRINCIPAL_INVESTIGATOR · The University of Texas Health Science Center, Houston
Who to contact
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What this trial measures
- Resting-state functional connectivity (rsFC) from functional magnetic resonance imaging (fMRI)1 month
The strength of rsFC from fMRI is used to represent the brain activities that are corresponding to the TMS effect on smoking reduction/cessation.
- Cigarette per day1 month
Cigarette per day (CPD) is measured to index smoking reduction and cessation.