SpeeDx Ciprofloxacin gyrA Assay for N. Gonorrhoeae Gonococcal Infection
This study is looking at how well ciprofloxacin (500 mg, taken once orally) works to treat Neisseria gonorrhoeae (a sexually transmitted infection, also called Ng or gonorrhea). Researchers want to see if using a special test called the SpeeDx Resistance Plus assay, which checks for a specific gene change (gyrA mutation) in the bacteria, can help decide if ciprofloxacin will be an effective treatment. You might be able to join if you are 18 or older, speak English, have internet access, and are getting routine STI screening without active symptoms. The study aims to see how many people with a specific type of Ng infection (gyrA wildtype) are cured with ciprofloxacin over two years. The study plans to enroll 1800 people and its current status is unclear.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 1800 participants.
- What's involved
- You will have specimens collected from areas of exposure for testing. If you are N. gonorrhoeae positive and have the gyrA wildtype, you will receive ciprofloxacin 500 mg orally once.
- Compensation
- Not stated in the trial record.
- Follow-up
- The effectiveness of the treatment will be measured at 2 years after receiving ciprofloxacin.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
SpeeDx Ciprofloxacin gyrA Assay for N. Gonorrhoeae Gonococcal Infection
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Lindley Barbee, MD, MPH · PRINCIPAL_INVESTIGATOR · University of Washington
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Determine the number and proportion of Neisseria Gonorrhea (NG) cases that can be cured with ciprofloxacin2 years
Number and proportion of patients who test positive for Neisseria Gonorrhea (NG) and are gyrA wildtype of all patients enrolled/screened for NG
- To determine the effectiveness of treating patients with Neisseria Gonorrhea gyrA wildtype with Ciprofloxacin 500 mg orally once2 years
Number and proportion of NG-positive patients with gyrA wildtype who are cured (i.e. have negative test of cure results) with 500mg ciprofloxacin overall and by anatomic site