This study is looking at a new way to prevent ovarian and fallopian tube cancer in women who have a high risk due to changes (mutations) in genes like BRCA1 or BRCA2. The study compares two procedures: the standard approach, called Risk-Reducing Salpingo-Oophorectomy (RRSO), which removes both the fallopian tubes and ovaries at the same time, and a new approach called Risk-Reducing Salpingectomy (RRS) with delayed Risk-Reducing Oophorectomy (RRO). This new approach removes the fallopian tubes first, and then the ovaries later. The goal is to see if the new approach is as effective as the standard one in preventing high-grade serous (a type of ovarian) cancer, while potentially delaying menopause. You may be able to join if you are a premenopausal woman with certain gene mutations and meet specific age requirements.

Study design

This is an interventional study planning to enroll 100 participants. It is a prospective preference study, meaning participants will choose between the two treatment options.

What's involved

You would complete questionnaires and have a standard-of-care laparoscopy (a surgical procedure to look inside the abdomen) before your assigned procedure.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint will be measured through study completion, which is an average of 15 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.