Music and Seizure Activity in Children with Epilepsy

This study is looking at whether listening to Mozart music or other age-appropriate instrumental songs can help reduce seizures and unusual brain activity (epileptiform discharges) in children with epilepsy. Researchers will play specific music through earbuds for short periods while children are staying in an Epilepsy Monitoring Unit (EMU). They will then compare changes in seizure frequency and brain activity to see if the music has a positive effect. The study aims to enroll 10 children aged 4 to 17 years old who are staying in an EMU. The study is currently unclear about its recruitment status.

Study design
This interventional study plans to enroll 10 participants. Music stimuli will be randomly played during the EMU stay.
What's involved
You would listen to Mozart K.448 and age-appropriate instrumental songs via earbuds for up to 9 minutes each, with a 10-minute break in between, during your EMU stay.
Compensation
Not stated in the trial record.
Follow-up
Changes in seizure activity will be measured during your Epilepsy Monitoring Unit stay, which can last up to 7 days.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05289934

Effects of Recorded Music on Clinical and EEG Seizure Activity

Recruiting
NAAges 4–17InterventionalTreatment
Johns Hopkins University
~10 participants
Updated 2026-03-06 on ClinicalTrials.gov
What's tested:Music Stimuli

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in the frequency of epileptiform discharges (number of spikes)
Measured over Epilepsy Monitoring Units Stay (up to Day 7)
+1 more outcome measured
Epilepsy
1 sites across 1 states
Maryland1
  • Sarah Kelley, MD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Children (age: 4 - 17 years old) who stay at Epilepsy Monitoring Units (EMU) up to 7 days may join.

Exclusion

Non-English Speaking
  • Change in the frequency of epileptiform discharges (number of spikes)Epilepsy Monitoring Units Stay (up to Day 7)

    The number of spikes in 100 seconds will be counted.

  • Change in the frequency of epileptiform discharges (number of seconds with spikes)Epilepsy Monitoring Units Stay (up to Day 7)

    The number of seconds with spikes will be measured.