Ketorolac and Triamcinolone Injections for Upper Extremity Pain

This study is looking at how well two different injections, ketorolac and triamcinolone, work for pain in your shoulder, elbow, wrist, or hand due to conditions like osteoarthritis (wear-and-tear arthritis) or tendinopathy (tendon problems). Triamcinolone is a corticosteroid that reduces inflammation, and ketorolac is an NSAID (non-steroidal anti-inflammatory drug) that also helps with inflammation. You might be able to join if you are 18 or older and have pain from these conditions, and haven't had surgery for them. The study will measure changes in your pain levels over 24 weeks to see which injection is more effective. The current recruitment status is unclear.

Study design
This study plans to enroll 160 participants. It is an interventional study, meaning participants will receive a specific treatment.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your pain levels will be checked at baseline, 6 weeks, and 24 weeks after the injection.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05292339

Ketorolac in Upper Extremity Tendinopathy and Arthropathy

Recruiting
PHASE4Ages 18+InterventionalTreatment
Emory University
~160 participants
Updated 2025-08-24 on ClinicalTrials.gov
What's tested:Triamcinolone injection to the shoulder, elbow, wrist, or handKetorolac injection to the shoulder, elbow, wrist, or hand

At a glance

Recruiting sites
4 of 4 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Changes in Visual Analog Scale (VAS) pain score
Measured over Baseline, 6 weeks, 24 weeks
Osteoarthritis
Tendinopathy
Arthropathy
4 sites across 1 states
Georgia4
  • Paul A. Ghareeb, MD · PRINCIPAL_INVESTIGATOR · Emory University
  • Amanda L Dempsey · PRINCIPAL_INVESTIGATOR · Emory University

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Eligibility criteria

Inclusion

Age 18 or older,
symptomatic tendinopathy or arthropathy of the shoulder, elbow, hand, or wrist who have not undergone prior surgical treatment for their condition.
Diagnoses may include trigger finger, De Quervain's tenosynovitis, radiocarpal osteoarthritis, first carpometacarpal (CMC) joint osteoarthritis, metacarpophalangeal joint osteoarthritis, or proximal interphalangeal joint osteoarthritis.

Exclusion

Patients under the age of 18,
Patients who have undergone prior triamcinolone or ketorolac injections within the past 6 months,
Patients who have undergone prior surgical treatment for their hand condition,
Patients with allergy or contraindication to triamcinolone or ketorolac injection,
Patients with an active infection at the treatment site \[active infection defined as cellulitis, purulence, fever, chills, or presence of elevated inflammatory markers, ie. white blood cells (WBC), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP)\].
  • Changes in Visual Analog Scale (VAS) pain scoreBaseline, 6 weeks, 24 weeks

    Participants will be asked to complete questionnaires to evaluate their pain at each follow-up visit. The visual analog scale or visual analog scale (VAS) is a psychometric response scale that can be used in questionnaires. It is a measurement instrument for subjective characteristics or attitudes that cannot be directly measured. When responding to a VAS item, respondents specify their level of agreement to a statement by indicating a position along a continuous line between two end-points. The Visual Analog Scale will be the subjective measurement to evaluate changes in pain scores, with values ranging from 0 (no pain) to 10 (very severe pain).