EyeConic Study for Retinal Dystrophies

This study, called EyeConic, is looking for people with inherited retinal dystrophies (eye conditions that cause vision loss) and healthy volunteers. The goal is to prepare for a future treatment that uses optogenetics to restore vision by making dormant (inactive) cone cells in the eye sensitive to light again. Researchers want to find out how many people with low vision still have these dormant cone cells. You would have an optical coherence tomography (OCT) scan, which is a special eye scan. This study is currently unclear on its recruitment status and aims to enroll 1000 participants.

Study design
This is an observational study involving 1000 planned participants. It includes both patients with inherited retinal dystrophies and healthy controls.
What's involved
You would need to have an optical coherence tomography (OCT) scan of your macula, which takes about 10 minutes at baseline.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05294978

EyeConic: Qualification for Cone-Optogenetics

Recruiting
Not specifiedAll AgesObservational
Institute of Molecular and Clinical Ophthalmology Basel
~1,000 participants
Updated 2025-07-31 on ClinicalTrials.gov
What's tested:Optical coherence tomography (OCT)

At a glance

Recruiting sites
9 of 9 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
OCT - Central retinal volume
Measured over Baseline (about 10 minutes)
Retinal Dystrophies
9 sites across 9 states
California1
Florida1
Pennsylvania1
China1
Germany1
Hungary1
Italy1
Switzerland1
  • Nicolas Feltgen, MD · PRINCIPAL_INVESTIGATOR · University Hospital Basel/Institute of Molecular and Clinical Ophthalmology Basel, Switzerland

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Diagnosis of generalized IRD
Low vision as defined as visual acuity worse or equal to 0.05 (or 20/400) in the study eye
Availability of macular optical coherence tomography (OCT)
Normal ophthalmic findings
Availability of macular optical coherence tomography (OCT)

Exclusion

Other eye diseases with a significant effect on vision or retinal structure
Extraocular disease affecting retinal structure such as neurodegenerative diseases
  • OCT - Central retinal volumeBaseline (about 10 minutes)

    Number of participants with preserved central retinal volume