Dexmedetomidine vs. Propofol for Sleep Endoscopy in Children with Sleep Apnea
This study is looking at two different medicines, dexmedetomidine and propofol, used for sedation during a drug-induced sleep endoscopy (DISE) procedure. DISE helps doctors see what's causing breathing problems during sleep in children with obstructive sleep apnea (OSA). Researchers want to see if one medicine is better at showing how the upper airway collapses. They also want to understand if certain collapse patterns are linked to OSA that continues even after surgery to remove tonsils and adenoids. Children aged 3 to 11 years with a confirmed OSA diagnosis can join. The main goal is to compare the amount of obstruction at the tongue base during the DISE procedure. The current recruitment status is unclear.
- Study design
- This is an interventional study planning to enroll 90 participants. Participants will receive either propofol or dexmedetomidine sedation after initial anesthesia.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint, mean obstruction score, is measured during the DISE procedure.
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Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Erin Kirkham, MD MPH · PRINCIPAL_INVESTIGATOR · University of Michigan
Who to contact
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What this trial measures
- Mean obstruction score at the tongue baseDuring Drug Induced Sleep Endoscopy (DISE) procedure, as judged subsequently by video review by the three raters
The degree of obstruction is scored on a 4-point scale as 0% (0), \<50% (1), 50-99% (2), or 100% (3). Scores from the 3 surgeons will be averaged for use in analysis.