Back to search results

Observational Study for Patients Undergoing Elective PCI

This study is looking at patients with stable coronary artery disease (CAD) who are having an elective PCI (percutaneous coronary intervention, a procedure to open blocked heart arteries). We want to see if a tool called the ABCD-GENE score can accurately predict which patients are at risk of having a heart attack or heart muscle injury (myocardial infarction or myocardial injury) after their PCI. These events can happen even with modern stents and are linked to poorer health outcomes. The study will measure your platelet reactivity (how sticky your blood platelets are) and troponin levels (a marker of heart damage) after your PCI. You may be able to join if you are 18 or older, have stable CAD, and are taking aspirin. Your troponin levels must be negative before your PCI.

Study design
This is an observational study with a planned enrollment of 500 participants. It is not a drug trial, but rather aims to validate a diagnostic tool.
What's involved
You will have your platelet reactivity and troponin levels measured after your PCI. The study does not specify additional visits or procedures beyond standard care.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome of peri-PCI myocardial infarction or myocardial injury will be measured at 24 hours after your procedure.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05332262

A Precision Medicine Approach to Identify Patients Undergoing Elective PCI at Risk of Peri-PCI Myocardial Infarction

Recruiting
Not specifiedAges 18+Observational
University of Florida
~500 participants
Updated 2026-01-20 on ClinicalTrials.gov
What's tested:Assessment of platelet reactivityTroponin measurement

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Peri-PCI myocardial infarction or myocardial injury
Measured over 24 hours

Conditions

Coronary Artery Disease

Explore related trials

Coronary Artery Disease

Where it's being run

1 sites across 1 states
Florida1

Study leadership

  • Francesco Franchi, MD · PRINCIPAL_INVESTIGATOR · University of Florida College of Medicine Jacksonville

Who to contact

Francesco Franchi, MD
[email protected]
9042442060
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

If troponin is unknown before coronary angiography and no clinical signs of acute coronary syndrome is present, a troponin will not be collected as this is line with standard practice.

What this trial measures

  • Peri-PCI myocardial infarction or myocardial injury24 hours

    The primary endpoint of the study will be rate of peri-PCI myocardial infarction or myocardial injury, which will be compared between the high ABCD-GENE score cohort and the low ABCD-GENE score cohort.