Understanding Stroke Recovery with TMS

This study, called VERIFY, is looking at how well different tools can predict recovery after a stroke, especially for arm and hand movement. Researchers are using a diagnostic test called Transcranial Magnetic Stimulation (TMS) to measure motor evoked potential (MEP) within the first week of hospitalization. They are also looking at MRI scans and clinical information. The goal is to see if these tools can accurately predict how much arm and hand function you might regain 90 days after a stroke. This information will help doctors better understand and personalize treatments for stroke survivors. You may be able to join if you are 18 or older and have had a stroke that affects one side of your body, causing weakness in your arm or hand. The study aims to include 657 participants, but its current status is unclear.

Study design
This is an observational study, meaning researchers will collect information without giving any new treatments. It plans to include 657 participants.
What's involved
The TMS procedure will be conducted during the first week of hospitalization. Your arm and hand function will be measured 90 days after your stroke.
Compensation
Not stated in the trial record.
Follow-up
Your arm and hand function will be measured 90 days after your stroke.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05338697

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

Recruiting
Not specifiedAges 18+Observational
Yale University
~657 participants
Updated 2026-08-20 on ClinicalTrials.gov
What's tested:Transcranial Magnetic Stimulation (TMS)

At a glance

Recruiting sites
40 of 45 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Upper Extremity-Fugl Meyer (UE-FM) for AIM 1
Measured over 90 days post-stroke
+1 more outcome measured
Stroke
Stroke, Acute
Stroke, Ischemic
45 sites across 23 states
California5
New York5
Massachusetts3
Pennsylvania3
Texas3
Wisconsin3
Alabama2
Illinois2
  • Pooja Khatri, MD · PRINCIPAL_INVESTIGATOR · Yale University
  • Steve Cramer, MD · PRINCIPAL_INVESTIGATOR · University of California, Los Angeles
  • Cathy Stinear, PhD · PRINCIPAL_INVESTIGATOR · University of Auckland, New Zealand
  • Achala Vagal, MD · PRINCIPAL_INVESTIGATOR · University of Cincinnati

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  • Upper Extremity-Fugl Meyer (UE-FM) for AIM 190 days post-stroke

    UE-FM score, as a continuous scale, adjusted for baseline score in analysis

  • Action Research Arm Test (ARAT) for AIM 290 days post-stroke

    ARAT categorized as 'excellent', 'good', 'limited', or 'poor'