Observational Study on Pulsatility During Cardiopulmonary Bypass
This study is looking at how the type of blood flow during cardiopulmonary bypass (a machine that takes over for your heart and lungs during surgery) affects your body after cardiac surgery. When you have heart surgery, a machine called a cardiopulmonary bypass machine helps circulate your blood. This machine can create blood flow that is either steady (non-pulsatile) or more like your natural heartbeat (pulsatile). Researchers want to see if one type of blood flow is better for your organs, specifically looking at endothelial function (how well the lining of your blood vessels works) and acute kidney injury (sudden kidney damage). You may be able to join if you are between 50 and 70 years old and are scheduled for elective cardiac surgery with cardiopulmonary bypass. The study will measure endothelial function from when you are admitted to the intensive care unit after surgery until you leave the hospital, up to 30 days.
- Study design
- This is an observational study with a planned enrollment of 66 participants. It will compare patients who receive pulsatile or non-pulsatile cardiopulmonary bypass during cardiac surgery.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed from intensive care unit admission after surgery to hospital discharge, up to 30 days.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Optimizing Pulsatility During Cardiopulmonary Bypass
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Nathan J Clendenen, MD, MS · PRINCIPAL_INVESTIGATOR · University of Colorado Denver | Anschutz
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Endothelial functionFrom intensive care unit admission after surgery to hospital discharge, up to 30 days
Percent change in flow mediated dilation of the brachial artery after cardiac surgery