Understanding Rare Cancers and Cancer Risk in Families
This observational study aims to understand why some people get cancer, focusing on rare tumors and family history. Researchers want to learn how genes (the instructions in our bodies) and environmental factors (things around us) can lead to cancer. You might be able to join if you have unusual tumors, a family history of cancer, or have been exposed to things that might increase cancer risk. The study will not involve any treatments. Instead, it will help define the natural course of cancers that run in families and identify genes that make people more susceptible to cancer. The goal is to understand these conditions better over many generations.
- Study design
- This is an observational study with a planned enrollment of 500 participants. It is not a treatment study.
- What's involved
- You will answer questions about your personal and family medical history. You will also give permission for researchers to look at your medical records.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed longitudinally to define the clinical spectrum and other manifestations associated with rare tumors and cancer predisposition syndromes. This follow-up is ongoing.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Rare Tumors and Cancer Predisposition in Individuals and Families
At a glance
Conditions
Where it's being run
2 sites across 1 statesStudy leadership
- Sharon A Savage, M.D. · PRINCIPAL_INVESTIGATOR · National Cancer Institute (NCI)
Who to contact
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What this trial measures
- Defining the natural history of familial cancers and susceptibility states over multiple generations, identifying cancer susceptibility genes, and assessing gene-environment and gene-gene interactionsOngoing
New cancer development or current health status