Recording of Intraoperative Spinal Cord Stimulation and Monitoring for Respiratory Function

This study is investigating whether epidural electrical stimulation (EES) of the cervical spinal cord (neck area) can help with breathing during surgery. Researchers believe EES might counteract the breathing problems caused by opioids, which are often used during surgery. You might be able to join if you are 18 or older and are having brain or spinal cord surgery where spinal neuromonitoring is used. The study will measure changes in your breathing rate and how much air you breathe in and out (tidal volume) during and shortly after the stimulation. The current status of this study is unclear.

Study design
This is an interventional study with a planned enrollment of 150 participants. It is not specified if it is randomized or blinded.
What's involved
Participants will receive epidural electrical stimulation during their intraoperative surgery. Respiratory function will be measured during and within 2 minutes after stimulation.
Compensation
Not stated in the trial record.
Follow-up
Respiratory function is measured during intraoperative surgery and within 2 minutes after stimulation. Further follow-up is not specified.

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NCT05356286

Recording of Intraoperative Spinal Cord Stimulation and Monitoring

Recruiting
NAAges 18+InterventionalTreatment
University of California, Los Angeles
~150 participants
Updated 2025-03-10 on ClinicalTrials.gov
What's tested:epidural electrical stimulation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in respiratory frequency
Measured over During intraoperative surgery during stimulation and within 2 minutes after stimulation
+1 more outcome measured
Cervical Stenosis
Disk, Herniated
Spondylosis
1 sites across 1 states
California1

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Eligibility criteria

Inclusion

Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized.

Exclusion

none
  • Change in respiratory frequencyDuring intraoperative surgery during stimulation and within 2 minutes after stimulation

    Increase or decrease in respiratory frequency of 20% during or after stimulation

  • Change in respiratory tidal volumeDuring intraoperative surgery during stimulation and within 2 minutes after stimulation

    Increase or decrease in respiratory tidal volume of 20% during or after stimulation