Observational Study for Early Cancer Detection Using cfDNA
This study is looking at a new blood test to find many types of cancer early and to see if cancer has returned after treatment. The test uses cell-free DNA (cfDNA), which are tiny pieces of DNA from cells that float in your blood. Researchers want to see if this test can accurately detect cancers like brain, breast, bladder, cervical, and colorectal cancer. They are also studying if it can find very small amounts of cancer remaining after treatment, especially for lung cancer. You can join if you are 40 or older and have been recently diagnosed with one of the listed cancers, or if you don't have cancer. The study aims to detect cancer within 24 months. The current recruitment status is unclear.
- Study design
- This is an observational study involving 7000 participants, including people with and without cancer. It is designed to compare the blood test results between these two groups.
- What's involved
- You will provide a blood sample and clinical information at the start. Some participants with lung cancer will have additional blood draws every 3-6 months for up to 3 years after treatment. Other participants may have yearly follow-up for 3 years.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants with certain cancers will have follow-up for up to 3 years after treatment. Control participants will have follow-up for up to 3 years to check for cancer status.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
At a glance
Conditions
Where it's being run
17 sites across 11 statesStudy leadership
- Brian Rini, MD · PRINCIPAL_INVESTIGATOR · Vanderbilt-Ingram Cancer Center
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Detection of cancer24 months
Differentiation of cancer signals from cases and non-cancer signals from controls based on analysis of cfDNA using the genome-wide methylome enrichment platform