Carnosine for Peripheral Arterial Disease

This study is looking at whether taking carnosine (2 grams per day) for three months can help men with Peripheral Arterial Disease (PAD) walk better. PAD is a condition where narrowed arteries reduce blood flow to your limbs, often causing leg pain when walking. Researchers believe carnosine might improve blood flow by helping new blood vessels grow (angiogenesis). The study will measure walking ability after one year. You may be eligible if you are a white or African American man between 50 and 80 years old, speak English, and have a specific ankle-brachial index (ABI) between 0.4 and less than 0.60. The study plans to enroll 20 participants.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 20 men.
What's involved
Participants will take carnosine daily for 3 months. The primary outcome will be measured at one year.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for one year after starting the carnosine supplementation.

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NCT05371145

Carnosine for Peripheral Arterial Disease Patients

UNKNOWN
PHASE1Ages 50–80InterventionalTreatment
Shahid Baba
~20 participants
Updated 2024-07-22 on ClinicalTrials.gov
What's tested:Carnosine

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Carnosine for Peripheral Arterial Disease patients
Measured over One year
Peripheral Arterial Disease
1 sites across 1 states
Kentucky1

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  • Carnosine for Peripheral Arterial Disease patientsOne year

    Compare the effects of carnosine supplementation on the 6-minute walk test (6MWT) at the baseline and after three months of carnosine supplementation. Measure the total walking distance and compare the walking distance covered by the subjects at the start and completion of carnosine supplementation