Sickle Cell Improvement: Enhancing Care in the Emergency Department

This study is looking at ways to improve care for children with sickle cell disease (SCD) when they visit the emergency department (ED) for a pain crisis. It's testing a "care pathway," which is a set of guidelines for how medical staff should manage these situations. The goal is to see if using this care pathway helps children receive pain medication (opioids) more quickly. You might be able to join if you are 18 years old or younger, have sickle cell disease, are visiting the ED for an uncomplicated pain crisis, and have received at least one opioid. You cannot join if you have acute chest syndrome, a fever over 38.5 degrees Celsius in the ED, priapism, or sickle cell trait. The study aims to enroll 5328 participants, but its current status is unclear.

Study design
This is an interventional study that plans to enroll 5328 participants. It is testing a care pathway as part of a hybrid type 2 implementation effectiveness study.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint measures the timeliness of receiving opioids, capturing all opioids received during the ED stay, up to a maximum of about 6 hours.

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NCT05373771

Sickle Cell Improvement: Enhancing Care in the Emergency Department

Recruiting
NAUp to 18InterventionalTreatment
Medical College of Wisconsin
~5,328 participants
Updated 2023-08-14 on ClinicalTrials.gov
What's tested:Care pathway

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Timeliness of receipt of opioids
Measured over A maximum of about 6 hours as all opioids received during the ED stay will be captured
Sickle Cell Crisis
1 sites across 1 states
Wisconsin1
  • David Brousseau, MD, MS · PRINCIPAL_INVESTIGATOR · Nemours Children's Health

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Eligibility criteria

Inclusion

ED visit for uncomplicated pain crisis
Sickle cell disease
Receipt of at least one opioid

Exclusion

Acute chest syndrome
Fever \> 38.5 in the ED
priapism
sickle cell trait
  • Timeliness of receipt of opioidsA maximum of about 6 hours as all opioids received during the ED stay will be captured

    The percent of patients who receive first dose of opioids within 60 minutes of arrival and subsequent doses within 30 minutes of previous dose