MET Non Small Cell Cancer Registry (MOMENT)

This registry is collecting information on people with advanced non-small cell lung cancer (NSCLC) that has a specific genetic change called METex14 skipping alterations. You could join if you have this type of cancer, have signed a consent form, and are starting or already receiving systemic therapy (treatment that affects the whole body). The registry aims to understand how treatments are changing and how well they work over time. Researchers will look at how your tumor responds to treatment (Best Overall Response and Tumor Response according to RECIST 1.1 criteria) and how long people live (Overall Survival) for up to about 4.9 years. This is an observational study, meaning you will receive your usual care, and no specific treatments are being tested.

Study design
This is an observational study collecting data from up to 700 participants. It is a disease registry, meaning it gathers information on a specific patient group over time without testing new treatments.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your health information will be collected for up to approximately 4.9 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05376891

Met Non Small Cell Cancer Registry (MOMENT)

Recruiting
Not specifiedAll AgesObservational
EMD Serono Research & Development Institute, Inc.
~700 participants
Updated 2026-08-17 on ClinicalTrials.gov

At a glance

Recruiting sites
72 of 79 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Best Overall Response (BOR)
Measured over Through study completion, up to approximately 4.9 years
+4 more outcomes measured
Cancer
79 sites across 20 states
United Kingdom13
France9
Spain9
Israel8
Italy8
Belgium4
Canada4
Germany4
  • Medical Responsible · STUDY_DIRECTOR · Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Participants who signed ICF
Participants with advanced stage (stages IIIB-IV) NSCLC (all histologies) and Confirmed METex14 skipping alterations (by valid assay)
Participants who are starting or are already being treated with systemic therapy

Exclusion

Participants who are enrolled in a clinical trial
  • Best Overall Response (BOR)Through study completion, up to approximately 4.9 years
  • Tumor Response According to Response Evaluation Criteria in Solid Tumors Version (RECIST) 1.1Up to approximately 4.9 years
  • Overall Survival (OS)Through study completion, up to approximately 4.9 years
  • Number of Participants with Adverse Events (AEs)Up to approximately 4.9 years
  • Number of Participants with Adverse Reactions (ARs)Up to approximately 4.9 years