This study is looking at whether oral ketamine can help children and young adults (ages 12-24) who are experiencing severe pain from a sickle cell crisis (vaso-occlusive crisis). Many patients with sickle cell disease have pain that isn't fully controlled by strong pain medicines like opioids. This study aims to see if giving oral ketamine, a different type of pain medicine, can be a helpful addition. All 10 participants will receive oral ketamine (0.5 mg/kg) every 8 hours for 48 hours while in the hospital. Researchers will measure changes in your pain intensity using a scale to see how well the treatment works. The study is also looking at how practical it is to give oral ketamine in this setting.

Study design

This is an interventional study with 10 participants, all of whom will receive oral ketamine. The study does not specify a phase or blinding.

What's involved

You would receive oral ketamine every 8 hours for 48 hours. Your pain scores, sedation levels, vital signs, and any side effects will be checked every 4 hours.

Compensation

Not stated in the trial record.

Follow-up

Your pain and side effects will be monitored for 48 hours during the study period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.