Preventing C. difficile in High-Risk Hospital Patients
This study is looking at ways to prevent Clostridioides difficile (C. difficile) infections in hospital patients. C. difficile is a common germ that can cause serious illness. Researchers want to see if a special "preemptive prevention bundle" can reduce the risk of infection in patients who already carry the C. difficile germ but don't have symptoms. These patients are identified through routine testing for another germ called vancomycin-resistant enterococcus (VRE). You might be able to join if you are an adult admitted to an ICU or Oncology unit and are found to carry C. difficile. The study will compare this special prevention bundle to the standard care patients usually receive, and will track infection rates for 24 months. The current status of this study is unclear.
- Study design
- This interventional study aims to enroll 300 participants. It compares a special prevention bundle to routine care for C. difficile.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 24 months to measure the risk of C. difficile infection.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Pre-emptive Prevention for Patients at High Risk for Hospital-onset Clostridioides Difficile
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Meghan A Baker, MD, SCD · PRINCIPAL_INVESTIGATOR · Brigham and Women's Hospital
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Risk of C. difficile infection among patients colonized with C. difficile comparing the intervention to the control group24 months
Incidence rate ratio of CDI in colonized patients who received the intervention bundle versus who did not receive the intervention bundle