Validation Study of Wearable Bioelectronic Sensors

This study is testing new, comfortable wearable sensors developed in a lab. These sensors, called Multi-modality Noninvasive Biosensors, are designed to continuously measure things like your heart rate, breathing, and blood flow. Researchers want to see if these new sensors are safe to wear and if they work as well as standard medical devices like an oximeter, a portable blood pressure monitor, and a Vicorder Pulse Wave Velocity Monitor. You can join if you are a healthy adult between 18 and 99 years old. The study aims to understand how comfortable and safe the new sensors are, and how well their measurements match those from approved devices. The current status of the study is unclear.

Study design
This interventional study plans to enroll 22 healthy participants. You will be randomly assigned to wear the devices for either 15 minutes before and after exercise, or for 2 hours continuously.
What's involved
You will have a 1-hour or 2.5-hour lab visit where you wear the sensors during activities like slow deep breathing and a brisk walk. You will also return for two brief follow-up visits 48 and 96 hours after wearing the devices.
Compensation
Not stated in the trial record.
Follow-up
You will have follow-up visits 48 and 96 hours after wearing the devices to check for any side effects.

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NCT05397951

The Validation Study of Bioelectronics

Recruiting
NAAges 18–99InterventionalScreening
University of North Carolina, Chapel Hill
~22 participants
Updated 2026-04-17 on ClinicalTrials.gov
What's tested:Multi-modality Noninvasive BiosensorOximeterPortable Blood Pressure MonitorVicorder Pulse Wave Velocity Monitor

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Mean Comfort Level of Wearable Sensors
Measured over Questionnaire completed within 96 hours after device application.
+2 more outcomes measured
Healthy
Health Behavior
1 sites across 1 states
North Carolina1
  • Wubin Bai, PhD · PRINCIPAL_INVESTIGATOR · Assistant Professor of Applied Physical Sciences

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Eligibility criteria

Inclusion

Individuals with ages between 18 and 99.
Healthy individuals (not known to suffer any significant illness relevant to the proposed study).

Exclusion

Pregnant or lactating.
History of active (clinically significant) skin disorders that make skin vulnerable to contact conventional electronic devices.
History of allergic response to silicones or adhesives (such as 3M Tegaderm).
Broken, damaged or irritated skin or rashes near the sensor application sites (finger, wrist, temple, subclavian, arm, neck, and thigh).
Subjects who are physically or cognitively unable to normally perform activities of daily living, assessed at the discretion of the investigator to ensure safe completion of study tasks.
Subjects who are unable to participate in moderate exercise for 6 minutes.
  • Mean Comfort Level of Wearable SensorsQuestionnaire completed within 96 hours after device application.

    A questionnaire about the comfort of the wearable sensors will be measured using the Likert scale, which ranges from 1 to 5 and is used to measure attitudes and perception changes about the our sensor. The minimum value 1 represents "strongly disagree" and the maximum value 5 represents "strongly agree", thus higher scores represent a better outcome.

  • Mean Safety Level of Wearable SensorsQuestionnaire completed within 96 hours after device application.

    A questionnaire about the safety and reactions to the wearable sensors will be measured using the Likert scale, which ranges from 1 to 5 and is used to measure attitudes and perception changes about the safety of our sensor. The minimum value 1 represents "strongly disagree" and the maximum value 5 represents "strongly agree", thus higher scores represent a better outcome.

  • Mean Agreement Over Time of Physiological Parameters between Newly-Fabricated Wearable Sensors and Approved DevicesThrough study completion, an average of 15 minutes.

    Signals from the approved medical devices will measure tissue mechanics, heart rate, respiration rate, blood flow, and pulse oxygenation measurements and these data will be compared to the signals from our sensors. The difference over time will be measured on a scale from a minimum of 0 and a maximum of 1, with 0 being the best outcome and representing the lowest difference between the sensing data from the different devices.