NCT05398250
A Comparison of Two Brief Suicide Prevention Interventions Tailored for Youth on the Autism Spectrum
Enrolling by Invitation
NAAges 12–99InterventionalTreatmentUniversity of North Carolina, Chapel HillInvestigator-initiated
~1,665 participants
Updated 2026-02-10 on ClinicalTrials.gov
What's tested:Safety Planning Intervention tailored for Autistic IndividualsSafety Planning Intervention Tailored for Autistic Individuals Plus Structured Follow-Up Contacts
At a glance
Recruiting sites
0 of 5 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in suicidal ideation and behavior
Measured over Through 12 months of follow-up
Conditions
Where it's being run
5 sites across 5 statesMaryland1
North Carolina1
Ohio1
Pennsylvania1
Washington1
Study leadership
- Danielle Roubinov, PhD · PRINCIPAL_INVESTIGATOR · University of North Carolina, Chapel Hill
- Shari Jager-Hyman, PhD · PRINCIPAL_INVESTIGATOR · University of Pennsylvania
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
12-24 years old
Receives one of the interventions being studied (SPI-A or SPI-A+) as part of routine clinical care
Referred to the study team by a consented clinician
Able and willing to provide informed consent (age 18+) or assent and parental/guardian consent (age \< 18)
Able to speak English (and, if applicable, at least one guardian also able to speak English)
Employment as a provider serving autistic patients at one of the study sites
Employment in a role that involves suicide risk intervention with youth patients at a participating clinic
Able to read and speak English
Able and willing to provide informed consent
Health system or clinic leader at one of the study sites
Employed in a role that provides administrative oversight to clinicians conducting safety plans with patients
Able to read and speak English
Able and willing to provide informed consent
What this trial measures
- Change in suicidal ideation and behaviorThrough 12 months of follow-up
The Columbia-Suicide Severity Rating Scale (C-SSRS) is a clinical interview that measures suicidal ideation (range 0-5, with higher scores indicating more severe ideation) and suicidal behavior (count of total number of actual attempts, interrupted attempts, aborted attempts, and preparatory acts or behavior). The C-SSRS will be administered at baseline, 1-month follow-up, 6-month follow-up, and 12-month follow-up.