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SPARC-C Study for Large Colon Polyps

The SPARC-C study is looking at how doctors manage large colon polyps (LNPCPs), which are growths in your colon. This study observes patients who are already receiving endoscopic tissue resection (a procedure to remove polyps using a scope) as part of their regular care. Doctors will be looking at how successful these procedures are right after they happen and then again six months later. You might be able to join if you are 18 or older and have been referred for treatment of a large colon polyp. This study is currently unclear on its recruitment status.

Study design
This is an observational study aiming to enroll 3500 participants. It is not a randomized study, meaning participants are not assigned to different treatment groups.
What's involved
Patients will undergo endoscopic tissue resection as part of their standard care. Data will be collected on your health details, the polyp, the procedure, and your outcomes.
Compensation
Not stated in the trial record.
Follow-up
Your clinical success will be measured at 6 months after the procedure.

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NCT05402696

St. Paul's Advanced Resection Center Cohort for Colorectal Neoplasia (SPARC-C)

Recruiting
Not specifiedAges 18+Observational
University of British Columbia
~3,500 participants
Updated 2026-05-15 on ClinicalTrials.gov
What's tested:Endoscopic tissue resection

At a glance

Recruiting sites
4 of 6 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Technical Success of Endoscopic Procedure
Measured over Intra-procedure
+1 more outcome measured

Conditions

Colon Adenoma
Colon Polyp
Colon Lesion

Explore related trials

Colon PolypColorectal Neoplasm

Where it's being run

6 sites across 3 states
British Columbia4
Minnesota1
Israel1

Who to contact

Shirley X Jiang, MD
[email protected]
(604) 688-6332
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patients ≥ 18 years of age referred for the management of an LNPCP
Able to provide informed consent.

Exclusion

Unable to provide informed consent
Pregnant or lactating women.

What this trial measures

  • Technical Success of Endoscopic ProcedureIntra-procedure

    Complete removal of all visible polypoid tissue during index procedure.

  • Clinical Success of Endoscopic Procedure6 months

    Technical success and the avoidance of surgery for large non-pedunculated colorectal polyps (LNPCPs) referred for endoscopic resection, assessed at first surveillance colonoscopy. LNPCPs with features consistent with invasive disease and directly referred for surgery are excluded.