Controls and Healthy Vasculature Initiative

This observational study, called the Controls and Healthy Vasculature Initiative, aims to collect blood samples from healthy volunteers. Researchers need these samples to understand what is normal in the body, especially concerning blood, blood vessels, and the immune system. This helps them develop and test new methods for studying diseases that affect these areas. There are no specific interventions or drugs being tested in this study. You may be able to join if you are a healthy adult between 18 and 90 years old. The main goal is to gather samples over a period of up to 10 years to help establish normal body functions and validate testing equipment for future research. The study is currently unclear on its recruitment status, but plans to enroll 1000 participants.

Study design
This is an observational study planning to enroll 1000 healthy participants. It is not testing a specific treatment or drug.
What's involved
You will have a telehealth visit or phone call to review your medical history, then come to the NIH Clinical Center for blood sample collection.
Compensation
Not stated in the trial record.
Follow-up
Samples will be collected for up to 10 years to establish normal physiologic mechanisms and parameters.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05403151

Controls and Healthy Vasculature Initiative

Recruiting
Not specifiedAges 18–90Observational
National Heart, Lung, and Blood Institute (NHLBI)
~1,000 participants
Updated 2026-09-04 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To collect samples from healthy volunteers to establish and validate technical assays and normal physiologic mechanisms and parameters for on-going and future basic and translational research studies.
Measured over Up to 10 Years
Vascular And Immunologic Diseases
Healthy Volunteers

NCT05403151

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • National Institutes of Health Clinical Center

    Bethesda, Marylandstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Yogendra Kanthi, M.D. · PRINCIPAL_INVESTIGATOR · National Heart, Lung, and Blood Institute (NHLBI)

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Stated willingness to comply with all study procedures
Aged 18 years and older
Ability of subject to understand and the willingness to sign a written informed consent document
Self-reported in good general health

Exclusion

Current pregnancy or lactation
  • To collect samples from healthy volunteers to establish and validate technical assays and normal physiologic mechanisms and parameters for on-going and future basic and translational research studies.Up to 10 Years

    This protocol does not have an outcome measure, but will obtain blood samples to optimize assays, conduct mechanistic investigations, measure vascular biomarkers, and facilitate the study of vascular and immunologic diseases in patients enrolled in other studies.