Positive Emotions Following Acute Cardiac Events

This study is testing a 12-week program called Positive Psychology + Motivational Interviewing (PP-MI) for people who have recently experienced an Acute Coronary Syndrome (ACS), like a heart attack or unstable angina. The program aims to improve your well-being and increase your physical activity through weekly phone sessions and activities. You might be able to join if you are 18-95 years old, have had an ACS, and are not very physically active. The study will compare the PP-MI program to usual care after an ACS to see if it helps you become more physically active over 24 weeks. The study is currently unclear on its recruitment status and plans to enroll 280 participants.

Study design
This is an interventional study comparing a 12-week intervention with usual care in 280 participants.
What's involved
You would complete weekly Positive Psychology activities, work towards physical activity goals, and have weekly phone sessions for 12 weeks. You would also receive text messages for 24 weeks and wear an accelerometer for one week at the start and at 24 weeks.
Compensation
Not stated in the trial record.
Follow-up
Your physical activity will be measured at 24 weeks after the start of the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05412862

Positive Emotions Following Acute Cardiac Events

Recruiting
NAAges 18–95InterventionalTreatment
Massachusetts General Hospital
~280 participants
Updated 2026-04-20 on ClinicalTrials.gov
What's tested:Positive Psychology + Motivational Interviewing

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from Baseline Moderate to Vigorous Physical Activity (MVPA) at 24 weeks
Measured over Measured for 7 days at baseline and 24 weeks
Acute Coronary Syndrome
Physical Inactivity

NCT05412862

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Massachusetts General Hospital

    Boston, Massachusettsstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Jeff C Huffman, M.D. · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital

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Eligibility criteria

Inclusion

ACS (myocardial infarction or unstable angina)
Suboptimal physical activity (score of \< 6 on the Medical Outcomes study Specific Adherence Scale item related to physical activity)

Exclusion

Cognitive deficits (assessed via a 6-item cognitive screening tool)
Medical conditions likely to lead to death within 6 months.
Moderate-severe depression (Patient Health Questionnaire-9 \[PHQ-9\] score ≥15)
Inability to participate in physical activity due to another medical condition (e.g., arthritis)
Inability to read, write, or speak in English
Inability to receive text-messages
Current participation in another intervention or program that has been designed to promote well-being or physical activity
  • Change from Baseline Moderate to Vigorous Physical Activity (MVPA) at 24 weeksMeasured for 7 days at baseline and 24 weeks

    MVPA will be measured via an accelerometer and recorded in mean minutes/day.