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Sentence Production Training for Aphasia

This study is testing a behavioral intervention called Sentence training for people with aphasia. Aphasia is a condition that affects your ability to communicate after a stroke. The training involves learning to read, create, and remember sentences. Researchers want to see if this training can improve your ability to produce and understand sentences. You might be able to join if you are 21 to 85 years old, had a stroke on the left side of your brain at least six months ago, are a native English speaker, and have difficulty speaking in sentences but can use words on their own. The study is currently unclear about its recruitment status and plans to enroll 104 participants.

Study design
This is an interventional study with a planned enrollment of 104 participants. It is not specified if the study is randomized or blinded.
What's involved
Participants will be trained to read, make, and recall sentences during each session. The duration of the training is not specified.
Compensation
Not stated in the trial record.
Follow-up
Your sentence production and comprehension will be measured from the start of the study up to one week after training or two months after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05415501

Sentence Production Training in Aphasia

Recruiting
NAAges 21–85InterventionalTreatment
Purdue University
~104 participants
Updated 2024-12-18 on ClinicalTrials.gov
What's tested:Sentence training

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Production of target sentences on action description pictures
Measured over From baseline up to 1-week post training or 2-month post treatment
+2 more outcomes measured

Conditions

Aphasia

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NCT05415501

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Purdue University

    West Lafayette, Indianastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Jiyeon Lee, PhD · PRINCIPAL_INVESTIGATOR · Purdue University

Who to contact

Jiyeon Lee, PhD
[email protected]
7654943810
Email the study team

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Eligibility criteria

Inclusion

Individuals with post-stroke aphasia
At least 6 months post-onset of eft hemisphere stroke
Native speaker of English
Normal or corrected to normal hearing and vision
High-school educated
Difficulty communicating in sentences, with some ability to use words independently

Exclusion

Severe apraxia of speech
Other neurological conditions affecting communication (e.g., dementia)
Uncontrolled psychiatric/psychological conditions affecting thinking and communication
Active alcohol/substance abuse

What this trial measures

  • Production of target sentences on action description picturesFrom baseline up to 1-week post training or 2-month post treatment

    Production accuracy (percent correct)

  • Comprehension of target sentences in a sentence-to-picture matching taskFrom baseline up to 1-week post training or 2-month post treatment

    Comprehension accuracy (percent correct)

  • Real-time comprehension of target sentences in a sentence-to-picture matching taskFrom baseline up to 1-week post training or 2-month post treatment

    Changes in eye fixations to the target picture