NCT05418959

Genetic Risk Stratification of Pediatric Skin Lesions

Enrolling by Invitation
PHASE1Ages 0–20InterventionalDiagnostic
Massachusetts General Hospital
~100 participants
Updated 2026-05-22 on ClinicalTrials.gov
What's tested:DermTech PLA noninvasive adhesive biopsy

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Presence or absence of PRAME genetic marker.
Measured over 1 day
+1 more outcome measured
Skin Lesion
Nevus
1 sites across 1 states
Massachusetts1
  • Elena B Hawryluk, MD, PhD · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

20 years of age or younger.
Subjects or parents willing and able to give informed consent, and assent as appropriate
Patients will have one or more atypical skin lesions with management plan of monitoring, surgical biopsy, and/or excision of atypical nevi within the next 6 months

Exclusion

Lesions on palms, soles, mucosal membranes, or area where hair cannot be trimmed
Bleeding or ulcerated lesions
Previously biopsied, scarred, or known melanoma lesions
Presence of active psoriasis/eczema/other skin condition in area to be biopsied
  • Presence or absence of PRAME genetic marker.1 day

    Presence or absence of PRAME genetic marker from PLA test

  • Presence or absence of LINC genetic marker.1 da7

    Presence or absence of LINC genetic marker from PLA test