Home-Based Exercise Tele-Rehabilitation After COVID-19

This study is testing a home-based exercise program called "Tele-exercise" for Veterans who have recovered from COVID-19. The program involves two remote exercise sessions per week, focusing on aerobic and resistance training. The goal is to see if this program can improve heart and lung fitness (cardiopulmonary function) and overall physical ability. You may be able to join if you are a Veteran between 50 and 85 years old, had COVID-19 over 90 days ago, and have certain health conditions like high blood pressure or diabetes. The study aims to enroll 80 participants. The current recruitment status is unclear.

Study design
This is an interventional study planning to enroll 80 participants. It is not specified if it is randomized or blinded.
What's involved
Participants will engage in exercise training twice a week at home for 12 weeks. The primary endpoint, VO2peak, will be measured at the beginning and after 12 weeks.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome is measured after 12 weeks of tele-exercise.

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NCT05425264

Home-Based Exercise Tele-Rehabilitation After COVID-19

Recruiting
NAAges 50–85InterventionalTreatment
VA Office of Research and Development
~80 participants
Updated 2025-11-10 on ClinicalTrials.gov
What's tested:Tele-exercise

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in VO2peak
Measured over Baseline and after 12 weeks tele-exercise
Post SARS-CoV2 (COVID-19)
1 sites across 1 states
Maryland1
  • Alice S. Ryan, PhD · PRINCIPAL_INVESTIGATOR · Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD

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Eligibility criteria

Inclusion

Veteran
documented COVID-19 \> 90 days ago
diagnosis of 2 of following conditions: hypertension, diabetes, cardiovascular disease, chronic kidney disease, chronic obstructive pulmonary disease OR 1 condition and BMI \> 30 kg/m2

Exclusion

myocardial infarction (within 3 months)
exertional or unstable angina (chest pain that limits activity)
severe congestive heart failure (EF \< 20% in last year or NYHA Classification III or IV)
uncontrolled hypertension (SBP \>180 \&/or DBP \> 110 mm Hg at screening)
screening EKG with ischemia, complex arrhythmia, or high-grade block (per Minnesota Code)
poorly controlled diabetes mellitus (FBS\>200 mg/dl, RBS \> 299 mg/dl, or HbA1C \> 10)
treatment for cancer except skin cancer (within 3 months)
peripheral vascular disease with claudication
severe arthritis limiting ambulation
neurologic disease limiting ambulation (weakness requiring assist device; severe neuropathy)
end stage liver disease (decompensated liver disease)
End stage renal failure (dialysis)
severe pulmonary disease (home O2, admission for dyspnea or pneumonia within 1 month)
high fall risk (history of falls, bone fracture)
dementia (based on Evaluation to Consent)
signs or symptoms of any medical comorbidity that would preclude exercise testing or training
exercises on routine basis (structured aerobic exercise \> 3 time per week)
  • Change in VO2peakBaseline and after 12 weeks tele-exercise

    physical fitness, units are ml/kg/min