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Language Processing and Transcranial Magnetic Stimulation (TMS) Study

This study is looking at how Transcranial Magnetic Stimulation (TMS) affects language processing in people who have had a stroke and developed aphasia (difficulty with language), as well as in healthy individuals. Researchers are using a device called Deymed DuoMag XT-100 rTMS. The goal is to see if TMS can change how quickly and accurately people perform language tasks. You might be able to join if you are between 18 and 85 years old, had a left hemisphere stroke at least one month ago, are right-handed, and speak fluent English. The study aims to enroll 135 participants, but its current recruitment status is unclear.

Study design
This interventional study will include healthy individuals and people with stroke and aphasia. It is designed as an active (or sham)-controlled, within-subject, randomized study.
What's involved
You will participate in language tasks immediately before and/or after TMS administration on the same day.
Compensation
Not stated in the trial record.
Follow-up
Your reaction time and accuracy on language tasks will be measured immediately before and/or after TMS administration on the same day.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05425615

Language Processing and TMS

Recruiting
NAAges 18–85InterventionalBasic science
Medical College of Wisconsin
~135 participants
Updated 2026-07-13 on ClinicalTrials.gov
What's tested:Transcranial Magnetic Stimulation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Reaction time on language task performance
Measured over Language tasks administered immediately before and/or after TMS administration (same day).
+1 more outcome measured

Conditions

Stroke
Aphasia
Language

Explore related trials

AphasiaStroke

NCT05425615

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Medical College of Wisconsin

    Milwaukee, Wisconsinstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Priyanka Shah-Basak, PhD · PRINCIPAL_INVESTIGATOR · Medical College of Wisconsin

Who to contact

Sidney Schoenrock
[email protected]
414-955-7579
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

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Eligibility criteria

Inclusion

Diagnosed with left hemisphere stroke
Consent date \>= 1 month after stroke onset
Right-handed
Fluent in English
18 years of age or older

Exclusion

Severe cognitive, auditory or visual impairments that would preclude cognitive and language testing
Non-decisional per decisionality questionnaire or other clinical assessment
Presence of major untreated or unstable psychiatric disease (e.g. schizophrenia, bipolar disease)
A chronic medical condition that is not treated or is unstable
Presence of
Pregnancy
History of skull fractures, or skin diseases
History of ongoing or unmanaged seizures or a family history of epilepsy
Presence of factors that potentially decrease seizure thresholds
On pro-convulsant medications
Untreated Sleep deprivation or insomnia
Ongoing alcoholism or illegal drug abuse (e.g., cocaine or MDMA users)
History of dyslexia or other developmental learning disabilities

What this trial measures

  • Reaction time on language task performanceLanguage tasks administered immediately before and/or after TMS administration (same day).

    Improvement on language task performance as measured by decrease in reaction time.

  • Accuracy on language task performanceLanguage tasks administered immediately before and/or after TMS administration (same day).

    Improvement on language task performance as measured by increase in accuracy.