NCT05426733

An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat in Children With Biliary Atresia

Enrolling by Invitation
PHASE3All AgesInterventionalTreatment
Albireo, an Ipsen Company
~180 participants
Updated 2026-07-02 on ClinicalTrials.gov
What's tested:Odevixibat

At a glance

Recruiting sites
0 of 30 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Proportion of patients who are alive and have not undergone liver transplant
Measured over From baseline to Week 104
Biliary Atresia
30 sites across 21 states
New York3
Turkey (Türkiye)3
Canada2
China2
Germany2
Italy2
Malaysia2
Colorado1

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Completion of the 104-week Treatment Period of Study A4250-011
Signed informed consent by caregiver

Exclusion

Patients who were not compliant with study drug treatment or procedures in Study A4250-011 as per the investigator's discretion
Any conditions or abnormalities which, in the opinion of the investigator, may compromise the safety of the patient, or interfere with the patient participating in or completing the study
Known hypersensitivity to any components of odevixibat
Patients who are scheduled for a liver transplant or are likely to require a liver transplant in the immediate future based on the investigator's judgment
  • Proportion of patients who are alive and have not undergone liver transplantFrom baseline to Week 104