This study is looking at whether a probiotic called *Lactobacillus sakei proBio65* can help treat chronic sinusitis (ongoing sinus inflammation) better than saline (saltwater) rinses. You might be able to join if you are 18 or older, have chronic sinusitis with worsening symptoms, and have had sinus surgery before. The study wants to enroll 60 people. Researchers will compare how well *Lactobacillus sakei proBio65* works against saline rinses by looking at your sinus symptoms after 6 weeks. The idea is that this probiotic might help by restoring the good bacteria in your sinuses and fighting off bad bacteria that cause infections.

Study design

This is a randomized, double-blind study, meaning participants and researchers won't know who is receiving the probiotic or the saline rinse. About 60 people will participate.

What's involved

Participants will use either the *Lactobacillus sakei proBio65* or saline nasal irrigation twice a day for 14 days.

Compensation

Not stated in the trial record.

Follow-up

Your sinus symptoms will be measured at 6 weeks after starting the treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.