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Respiratory Training for Anxiety Disorders

This study is looking into a treatment called Capnometry-Guided Respiratory Intervention (CGRI) for people with anxiety disorders like Generalized Anxiety Disorder, Panic Disorder, or Agoraphobia. CGRI uses a device to help you learn to breathe in a way that can reduce anxiety symptoms. Researchers want to see if CGRI works better than or as well as psycho-education (learning about anxiety and its effects). To join, you need to be 18 or older and have significant anxiety. The study will measure your anxiety levels at the start, after treatment, and then 2 months later to see how well the treatments worked. The current status of the study is unclear.

Study design
This is a randomized study comparing two groups of participants. It plans to enroll 180 people.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your anxiety levels will be checked at the start, after 5 weeks of treatment, and then again 2 months later (at Week 13).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05427708

Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety

Recruiting
NAAges 18+InterventionalTreatment
University of Texas at Austin
~180 participants
Updated 2025-08-24 on ClinicalTrials.gov
What's tested:Capnometry-Guided Respiratory InterventionPsycho-Education

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Overall Anxiety Severity and Impairment Scale
Measured over Pre-Treatment (Week 0), Post-treatment (Week 5), 2-Month Follow-Up (Week 13)
+1 more outcome measured

Conditions

Anxiety Disorders
Trauma
Generalized Anxiety Disorder
Panic Disorder
Agoraphobia
Illness Anxiety Disorder
Social Anxiety Disorder
Posttraumatic Stress Disorder
Acute Stress Disorder
Adjustment Disorder With Anxious Mood

Explore related trials

Acute Stress DisorderAdjustment DisorderAgoraphobiaGeneralized Anxiety DisorderIllness anxiety disorderPanic DisorderPost-Traumatic Stress DisorderSocial Anxiety Disorder

Where it's being run

1 sites across 1 states
Texas1

Who to contact

Michael J Telch, PhD
[email protected]
512-814-5480
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Generalized Anxiety Disorder
Panic Disorder
Health Anxiety
Agoraphobia
Social Anxiety Disorder
Posttraumatic Stress Disorder
Acute Stress Disorder
Adjustment Disorder with primary anxious mood
Anxiety disorder not otherwise specified 3. No current use of psychotropic medications or stable on current medications for at least 6 weeks 4. Age 18+. 5. Able to arrange transportation to our laboratory for study appointments. 6. Fluent in English.

Exclusion

Cardiovascular or respiratory disorders
High blood pressure
Epilepsy
Strokes
Seizures
History of fainting
Pregnant or lactating 2. Not currently receiving other psychological treatment for anxiety. 3. No history of a suicide attempt within the past 6 months. 4. No history of psychosis within the past 6 months. 5. No history of moderate to severe alcohol or substance use disorder (with the exception of nicotine) within the past 3 months. 6. Does not endorse COVID-19 symptoms during the screening phase.

What this trial measures

  • Overall Anxiety Severity and Impairment ScalePre-Treatment (Week 0), Post-treatment (Week 5), 2-Month Follow-Up (Week 13)

    Change from baseline in self-reported transdiagnostic anxiety symptoms (range = 0 - 20, with higher scores indexing more symptoms).

  • Computerized Hamilton Anxiety ScalePre-Treatment (Week 0), Post-treatment (Week 5), 2-Month Follow-Up (Week 13)

    Change from baseline in anxiety symptom severity. Each item is assessed both in terms of frequency and severity. Scores on these probes are summed and divided by the number of response options. Higher scores index higher severity.