Study of THC and Beta-Myrcene in Cannabis Use

This study is looking at how pure THC (the main active ingredient in cannabis) and pure beta-myrcene (a compound found in cannabis) affect people when vaporized. You might be able to join if you are between 18 and 55 years old, in good health, and use cannabis but no other drugs. The researchers want to see how these substances, alone and together, impact your self-reported drug effects, which will be measured after 6 hours. The current recruitment status is unclear.

Study design
This study plans to enroll 32 participants. It uses a placebo-controlled, within-subject crossover design, meaning each participant will try all treatments, including placebo, in a random order.
What's involved
You will complete 9 separate drug administration periods where you will inhale different vapors. Subjective drug effects and vital signs will be checked after each administration.
Compensation
Not stated in the trial record.
Follow-up
Self-reported drug effects will be measured at 6 hours after drug administration.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05432284

Behavioral Pharmacology of THC and Beta-Myrcene

Not Yet Recruiting
PHASE1Ages 18–55InterventionalBasic science
Johns Hopkins University
~32 participants
Updated 2026-07-31 on ClinicalTrials.gov
What's tested:PlaceboTHCBeta-Myrcene

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Self-reported Drug Effect as assessed by the Drug Effect Questionnaire (DEQ)
Measured over 6 hours
Cannabis Use
1 sites across 1 states
Maryland1
  • Ryan Vandrey, PhD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University

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  • Self-reported Drug Effect as assessed by the Drug Effect Questionnaire (DEQ)6 hours

    Peak rating (0-100) of Drug Effect on the DEQ, with 0 being no effect and 100 being maximum effect.