This study, called the Prehospital Analgesia INtervention (PAIN) trial, is looking at the best way to manage pain for people with traumatic injuries before they get to the hospital. Researchers want to compare two pain medications: ketamine hydrochloride and fentanyl citrate. You might be able to join if you're at least 18 years old, are being transported to a participating trauma center after an injury, have signs of compensated shock (like a fast heart rate), and need pain medication. The main goal is to see if one medication leads to better patient outcomes, specifically looking at survival within 24 hours of arriving at the trauma bay. The study plans to enroll about 994 patients, but its current status is unclear.

Study design

This is a randomized, double-blind study, meaning participants will be randomly assigned to receive either ketamine hydrochloride or fentanyl citrate, and neither you nor your doctors will know which one you're getting. It plans to enroll about 994 participants.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

The study will track your survival for 24 hours after you arrive at the trauma bay.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.