Observational Study of Ovarian Tissue Cryopreservation (OTC) for Fertility Preservation

This observational study is creating a databank of human ovarian tissue from individuals who undergo ovarian tissue cryopreservation (OTC). OTC is a procedure where ovarian tissue is frozen before treatments that might cause infertility, such as cancer therapies. The goal is to understand the normal structure and function of human ovaries. Researchers will also collect de-identified information to learn about the short-term and long-term effects of OTC, including future pregnancies. This study is for women aged 4 to 35 years who are undergoing OTC. The study aims to enroll 100 participants. The current recruitment status is unclear.

Study design
This is an observational study with a planned enrollment of 100 participants. It is not a clinical trial testing a new treatment.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is creating a databank of human ovarian tissue, measured at the end of the study. Long-term outcomes, including reproductive health, will also be studied.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05440617

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

Recruiting
Not specifiedAges 4–35Observational
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
~100 participants
Updated 2026-08-28 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
create a databank of human ovarian tissue
Measured over end of study
Acute Ovarian Failure
Infertility
Early Menopause And Infertility In Females After Treatment For Childhood Cancer
1 sites across 1 states
Maryland1
  • Veronica Gomez-Lobo, M.D. · PRINCIPAL_INVESTIGATOR · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Provision of signed and dated informed consent/assent form.
Stated willingness to comply with all study procedures and availability for the duration of the study.
Subjects who have planned to undergo OTC for gonadotoxic therapy based on current standard of care.

Exclusion

An individual who meets any of the following criteria will be excluded from participation in this study:
Adults subjects with psychological, psychiatric, or other conditions which prevent giving fully informed consent.
  • create a databank of human ovarian tissueend of study

    Create a databank of human ovarian tissue to elucidate histology and function in human ovaries