Coconut Oil to Prevent Mouth Sores in Children Receiving Chemotherapy
This study is looking at whether virgin coconut oil (VCO) mouth rinse can help prevent oral mucositis (mouth sores) in children and young adults receiving high-dose chemotherapy. Participants aged 7 to 26 years will either receive standard mouth rinses or standard rinses plus virgin coconut oil mouth rinse. Researchers will compare the severity of mouth sores between these two groups after 45 days. The study aims to enroll 60 participants, but its current recruitment status is unclear.
- Study design
- This is a randomized, open-label study planning to enroll 60 participants. It compares two groups: standard care with virgin coconut oil mouth rinse, and standard care alone.
- What's involved
- Participants will use their assigned mouth rinse from the start of their hospital admission for conditioning until 45 days after transplant or hospital discharge, whichever comes first.
- Compensation
- Not stated in the trial record.
- Follow-up
- A safety follow-up visit will occur no sooner than 30 days after the last study treatment.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Coconut Oil to Prevent Mouth Sores in Pediatric Patients Receiving High Dose Chemotherapy
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Courtney Huddle, DCN, RDN, CSPCC, LDN · PRINCIPAL_INVESTIGATOR · Wake Forest University Health Sciences
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Severity of MucositisDay 45
Using Area Under the Curve (AUC) of the Common Terminology Criteria for Adverse Events (CTCAE) version 5.0 mucositis oral grading scale. This is a 5-point ordered-categorical scale ranging from 1 (asymptomatic or mild symptoms) to 5 (death). For subjects not experiencing oral mucositis, a severity grade of zero will be assigned.