Low-dose Buprenorphine Initiation for Opioid Use Disorder
This study is testing if a low-dose way to start buprenorphine-naloxone (a medication for opioid use disorder) is safe and works well. You could join if you are 18 or older, have Opioid Use Disorder, and can take medicine under your tongue. The study will compare this low-dose approach to the standard way of starting buprenorphine-naloxone over two days. The main goal is to see how many people who are assessed actually join the study. The current status of this study is unclear, and it plans to enroll about 70 people.
- Study design
- This is an interventional study that will randomly assign participants to one of two treatment groups. Approximately 70 participants are planned for enrollment.
- What's involved
- You would have study visits at the beginning, and then at weeks 2 and 4. You would also use a mobile phone to report information about withdrawal, anxiety, craving, and substance use.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will have study visits at baseline, week 2, and week 4.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Low-dose Buprenorphine Initiation for Opioid Use Disorder
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Benjamin T Hayes, MD, MS, MPH · PRINCIPAL_INVESTIGATOR · Montefiore Medical Center
Who to contact
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What this trial measures
- Recruitment Feasibility: Percentage of subjects assessed who enroll in the clinical trial.At baseline study visit (time zero)
This pilot study is designed to establish the feasibility of a future, full-powered clinical trial. The primary question this study seeks to answer is whether primary care patients with opioid use disorder are willing to enroll in a clinical trial of low-dose inductions. The study will aim to enroll 25% of subjects who are assessed. "Assessed" is defined as having been referred to the study staff. Enrollment is defined as having been randomized to a treatment arm.