Observational Study on Vaping and Blood Vessel Health
This study aims to understand how vaping affects your blood vessels, especially those in your lungs, and if it causes early damage. Researchers are looking for two groups of people: current electronic cigarette (EC) Puff Bar users (using 5% nicotine daily or occasionally for at least 6 months) and healthy individuals who have never smoked or vaped. Both groups should be between 18 and 40 years old. The study will measure changes in your airway blood flow reactivity (QAW), pulmonary vascular resistance (PVR - a measure of blood flow resistance in the lungs), and flow-mediated vasodilation (FMD - how well your blood vessels widen) to see if vaping has an impact. The study plans to enroll 90 participants.
- Study design
- This is an observational study, meaning researchers will observe participants without providing any specific interventions. It plans to enroll 90 participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Measurements will be taken up to 1 week for airway blood flow reactivity and up to 4 weeks for pulmonary vascular resistance and flow-mediated vasodilation.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Early Detection of Vaping-related Vascular Diseases
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Adam Wanner, MD · PRINCIPAL_INVESTIGATOR · University of Miami
Who to contact
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What this trial measures
- Airway blood flow reactivity (QAW)Up to 1 week
QAW will be measured via soluble gas uptake method
- Pulmonary vascular resistance (PVR)Up to 4 weeks
PVR will be measured via echocardiography
- Flow-mediated vasodilation (FMD)Up to 4 weeks
FMD will be measured by blood pressure cuff deflation using ultrasound