Intravenous Caffeine and Atrial Fibrillation Study
This study is looking at how intravenous (IV) caffeine affects the electrical properties of the heart in people who have Atrial Fibrillation (AF), a type of irregular heartbeat. Researchers want to understand if caffeine makes AF more likely to happen. You would receive either IV caffeine or a placebo (a substance with no active medicine, like sugar water) during a procedure for your AF. The study aims to see how many participants experience AF induction (when AF is triggered) within one day. This study is for adults aged 21 to 90 who have new or recent AF and are having an AF ablation procedure. The current status of the study is unclear.
- Study design
- This is a multi-center, randomized, double-blinded study comparing intravenous caffeine to a placebo. It plans to enroll 100 participants.
- What's involved
- You would receive an intravenous infusion of either caffeine or a placebo during an Atrial Fibrillation ablation procedure.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be monitored for Atrial Fibrillation induction for one day after the intervention.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Impact of Intravenous Caffeine on Atrial Electrical Properties and Potential Arrythmia Induction
At a glance
Conditions
NCT05464940
Where you'd take part
This study runs at 9 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Centerpoint Medical Center
Independence, Missourino site contact published
Centerpoint Medical Center Clinic
Independence, Missourino site contact published
Kansas City Heart Rhythm Institute
Overland Park, Kansasno site contact published
Loma Linda University
Loma Linda, Californiano site contact published
Menorah Medical Center
Overland Park, Kansasno site contact published
Overland Park Regional Medical Center
Overland Park, Kansasno site contact published
Research Medical Center
Kansas City, Missourino site contact published
Research Medical Center Clinic
Kansas City, Missourino site contact published
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Dhanunjaya Lakkireddy · PRINCIPAL_INVESTIGATOR · Kansas City Heart Rhythm Institute
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Number of Participants With Atrial Fibrillation Induction1 day
Induction of Atrial fibrillation will be attempted by pacing and isoproterenol infusion following study drug infusion. The ability to induce atrial fibrillation (yes or no) will be recorded as the primary outcome.