Exercise in Metastatic Breast Cancer: EMBody

{ "Exercise in Metastatic Breast Cancer: EMBody", "This study, called EMBody, is looking at how exercise affects people with metastatic breast cancer (cancer that has spread) that has not progressed in the last 12 months. Researchers want to see if a 16-week exercise program can improve your heart and lung fitness, physical abilities, and overall well-being. You could join if you are 18 or older, have metastatic breast cancer, and your disease hasn't gotten worse in the past year. The study aims to enroll up to 100 participants to compare the exercise program to usual care. The main goal is to see if exercise significantly improves your cardiorespiratory fitness (how well your heart and lungs work during exercise).", "design": "This is a randomized study with two groups, involving up to 100 participants. You would be randomly assigned to either the exercise program or usual care.", "commitments": "If you are in the exercise group, you will work with an exercise trainer three times a week for 16 weeks, with each session lasting 60 minutes. Your cardiorespiratory fitness will be measured at the beginning and after 16 weeks.", "compensation": "Not stated in the trial record.", "follow_up": "Your cardiorespiratory fitness will be measured at baseline and again after 16 weeks.", }

Study design
Not specified.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05468034

Exercise in Metastatic Breast Cancer: EMBody

Recruiting
NAAges 18+InterventionalSupportive care
Indiana University
~100 participants
Updated 2026-04-27 on ClinicalTrials.gov
What's tested:Exercise Intervention

At a glance

Recruiting sites
2 of 6 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in cardiorespiratory fitness
Measured over baseline, 16 weeks
Breast Cancer
Indolent Metastatic Breast Cancer
6 sites across 3 states
Indiana4
Connecticut1
Massachusetts1
  • Tarah Ballinger, MD · PRINCIPAL_INVESTIGATOR · Indiana University

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Eligibility criteria

Exclusion

NYHA class III or IV congestive heart failure
Uncontrolled angina
Myocardial infarction in the prior 12 months
Orthopedic surgery in the previous 3 months or plans for orthopedic surgery during the study period
Chronic uncontrolled pulmonary conditions such as uncontrolled asthma (symptoms \> 2 days/week) or dyspnea requiring oxygen
Symptomatic peripheral vascular disease
Or any other comorbidity that would interfere with the ability to complete and comply with the protocol in the opinion of the investigator, including psychological illness
History of fragility fracture 3. Active, untreated brain metastases
  • Change in cardiorespiratory fitnessbaseline, 16 weeks

    Measured by minutes on the treadmill