FAAN-C Trial: Comparing Follow-up Approaches for Children After Hospitalization

This study, called the FAAN-C trial, is looking at the best way for children to follow up with doctors after being hospitalized for common infections like pneumonia, urinary tract infections, skin infections, or stomach flu (gastroenteritis). We are comparing two approaches: 1. **As-needed follow-up:** You'll be told that scheduling a follow-up visit isn't immediately necessary, and you can decide if your child needs one based on their symptoms. 2. **Automatic follow-up:** You'll be asked to schedule and attend a follow-up visit even if your child feels better. The main goal is to see if one approach leads to fewer children being readmitted to the hospital within 14 days of discharge. To join, your child must be under 18 and have been hospitalized for one of these infections, and a parent must speak English or Spanish. The study is currently unclear on its recruitment status, but aims to enroll 2674 participants.

Study design
This is a multicenter randomized controlled trial, meaning participants will be randomly assigned to one of the two follow-up approaches. The study plans to enroll 2674 children.
What's involved
Participants will receive a recommendation at hospital discharge for either as-needed or automatic follow-up. The automatic follow-up group will be instructed to schedule and attend a follow-up visit.
Compensation
Not stated in the trial record.
Follow-up
The study will measure hospital readmission within 14 days of hospital discharge.

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NCT05471908

Follow-up Automatically vs. As-Needed Comparison (FAAN-C) Trial

Recruiting
NAUp to 18InterventionalHealth services
University of Utah
~2,674 participants
Updated 2025-12-10 on ClinicalTrials.gov
What's tested:As-needed follow upAutomatic follow-up

At a glance

Recruiting sites
13 of 14 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Hospital readmission
Measured over Within 14 days of hospital discharge
Pneumonia
Urinary Tract Infections
Soft Tissue Infections
Gastroenteritis
14 sites across 9 states
Utah3
California2
Ohio2
Texas2
Arizona1
Missouri1
New Jersey1
Pennsylvania1
  • Eric Coon, MD · PRINCIPAL_INVESTIGATOR · University of Utah

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Eligibility criteria

Inclusion

Age \<18 years at the time of randomization
Hospitalization due to a primary diagnosis of pneumonia, skin and soft tissue infection, acute gastroenteritis, or urinary tract infection.
Parent speaks English or Spanish.

Exclusion

Presence of a comorbid disease that is both chronic and complex
Principal disease required surgical intervention (beyond superficial incision and drainage)
Immunodeficiency
A well-child check-up or post-hospitalization follow-up visit is already scheduled within 7 days of hospital discharge
Parent or participant strongly prefers PRN or automatic follow-up
A medical provider feels strongly that a post-hospitalization follow-up visit is needed within 7 days of hospital discharge
Sibling concurrently hospitalized
Unable to identify a clinic where the participant would receive any needed post-hospitalization follow-up
Diagnosis of pneumonia complicated by:
Diagnosis of urinary tract infection complicated by:
History of neurogenic bladder or urologic surgery
Renal imaging anticipated within 7 days of hospital discharge
Renal abscess
Diagnosis of skin and soft tissue infection complicated by:
Chronic wound
Postoperative infection
Predisposition to poor wound healing
Discharging with a drain in place
Complicated by necrotizing fasciitis or toxic shock syndrome
Diagnosis of gastroenteritis complicated by:
Hemolytic uremic syndrome
  • Hospital readmissionWithin 14 days of hospital discharge

    The proportion of participants who experience a hospital readmission within 14 days of their index hospital discharge.