NCT05472597

Continuation of the nuMoM2b Heart Health Study

Enrolling by Invitation
Not specifiedAges 18+Observational
RTI International
~4,048 participants
Updated 2026-07-01 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 14 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Incidence of hypertension (130/80 mmHg)
Measured over Assessed during the HHS2 in-person visit, 8-16 years after the index pregnancy.
+3 more outcomes measured
Cardiovascular Diseases

NCT05472597

Where you'd take part

This study runs at 14 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Case Western Reserve University/The MetroHealth System

    Cleveland, Ohiono site contact published

  • Christiana Care Health Services

    Newark, Delawareno site contact published

  • Columbia University Medical Center

    New York, New Yorkno site contact published

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvaniano site contact published

  • Indiana University

    Indianapolis, Indianano site contact published

  • Intermountain Medical Center

    Murray, Utahno site contact published

  • LDS Hospital

    Salt Lake City, Utahno site contact published

  • Magee Womens Research Institute

    Pittsburgh, Pennsylvaniano site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • George Saade, MD · PRINCIPAL_INVESTIGATOR · Old Dominion University
  • Phillip Greenland, MD · PRINCIPAL_INVESTIGATOR · Northwestern University
  • Rebecca McNeil, PhD · PRINCIPAL_INVESTIGATOR · RTI International

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Completed one or more interval contacts during the nuMoM2b Heart Health Study.
Able to speak or read in English or Spanish.
Completed one or more interval contacts during the nuMoM2b Heart Health Study.
At least 18 years of age.
Self-report of at least 3 months postpartum from any subsequent pregnancy.
Provision of signed informed consent for the HHS2 study visit.
Able to speak or read English or Spanish.

Exclusion

Withdrawal from study.
Current pregnancy.
Withdrawal from study.
  • Incidence of hypertension (130/80 mmHg)Assessed during the HHS2 in-person visit, 8-16 years after the index pregnancy.

    Measured blood pressure \> 130/80 mmHg, use of antihypertensive medication, or self-report of a hypertension clinical diagnosis

  • Incidence of diabetesAssessed during the HHS2 in-person visit, 8-16 years after the index pregnancy.

    Measured hemoglobin A1c GE 6.5%, fasting blood glucose GE 126 mg/dL, use of blood sugar lowering medication, or self-report of a diabetes clinical diagnosis

  • Incidence of obesityAssessed during the HHS2 in-person visit, 8-16 years after the index pregnancy.

    Measured BMI GE 30 kg/m\^2

  • Incidence of metabolic syndromeAssessed during the HHS2 in-person visit, 8-16 years after the index pregnancy.

    Per the American Heart Association standard definition: Any three of the following five - 1) waist circumference \> 35 inches (88 cm) for non-Asians and \> 31.5 inches (80 cm) for Asians; 2) triglycerides \> 150 mg/dL or medication treatment for high triglycerides; 3) high density lipoprotein (HDL) \< 50 mg/dL or medication treatment for low HDL; 4) a serum glucose ≥ 100 mg/dL or a diagnosis of diabetes mellitus; 5) systolic blood pressure (SBP) ≥ 130 mmHg or diastolic blood pressure (DBP) ≥ 85 mmHg, or medication treatment for hypertension.