NCT05472597

Continuation of the nuMoM2b Heart Health Study

Enrolling by Invitation
Not specifiedAges 18+Observational
RTI International
~4,048 participants
Updated 2026-07-01 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 14 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Incidence of hypertension (130/80 mmHg)
Measured over Assessed during the HHS2 in-person visit, 8-16 years after the index pregnancy.
+3 more outcomes measured
Cardiovascular Diseases
14 sites across 8 states
Utah5
Pennsylvania3
California1
Delaware1
Illinois1
Indiana1
New York1
Ohio1
  • George Saade, MD · PRINCIPAL_INVESTIGATOR · Old Dominion University
  • Phillip Greenland, MD · PRINCIPAL_INVESTIGATOR · Northwestern University
  • Rebecca McNeil, PhD · PRINCIPAL_INVESTIGATOR · RTI International

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Completed one or more interval contacts during the nuMoM2b Heart Health Study.
Able to speak or read in English or Spanish.
Completed one or more interval contacts during the nuMoM2b Heart Health Study.
At least 18 years of age.
Self-report of at least 3 months postpartum from any subsequent pregnancy.
Provision of signed informed consent for the HHS2 study visit.
Able to speak or read English or Spanish.

Exclusion

Withdrawal from study.
Current pregnancy.
Withdrawal from study.
  • Incidence of hypertension (130/80 mmHg)Assessed during the HHS2 in-person visit, 8-16 years after the index pregnancy.

    Measured blood pressure \> 130/80 mmHg, use of antihypertensive medication, or self-report of a hypertension clinical diagnosis

  • Incidence of diabetesAssessed during the HHS2 in-person visit, 8-16 years after the index pregnancy.

    Measured hemoglobin A1c GE 6.5%, fasting blood glucose GE 126 mg/dL, use of blood sugar lowering medication, or self-report of a diabetes clinical diagnosis

  • Incidence of obesityAssessed during the HHS2 in-person visit, 8-16 years after the index pregnancy.

    Measured BMI GE 30 kg/m\^2

  • Incidence of metabolic syndromeAssessed during the HHS2 in-person visit, 8-16 years after the index pregnancy.

    Per the American Heart Association standard definition: Any three of the following five - 1) waist circumference \> 35 inches (88 cm) for non-Asians and \> 31.5 inches (80 cm) for Asians; 2) triglycerides \> 150 mg/dL or medication treatment for high triglycerides; 3) high density lipoprotein (HDL) \< 50 mg/dL or medication treatment for low HDL; 4) a serum glucose ≥ 100 mg/dL or a diagnosis of diabetes mellitus; 5) systolic blood pressure (SBP) ≥ 130 mmHg or diastolic blood pressure (DBP) ≥ 85 mmHg, or medication treatment for hypertension.