Observational Study on CF Carrier State and Organ Health
This observational study is looking into whether being a carrier for cystic fibrosis (CF) might increase the risk of developing certain health issues, specifically affecting the pancreas and kidneys. Researchers believe that CF carriers might show early, subtle signs of these conditions compared to people who are not CF carriers. The study aims to compare glucose (blood sugar) and insulin levels between CF carriers and non-carriers. You could be eligible if you are between 18 and 100 years old and are a confirmed CF carrier or have never been tested for CF. You cannot participate if you have CF, are pregnant, or are taking diabetes medication. The study involves one clinic visit where you'll answer questions and have lab tests. Some participants will also collect urine and stool samples at home.
- Study design
- This is an observational study planning to enroll 1250 participants. It compares health markers in CF carriers to those who are not CF carriers.
- What's involved
- You will have one clinic visit for measurements, blood pressure, blood draws, and a 2-hour oral glucose tolerance test. Some participants will also collect urine and stool samples at home.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary measurements for glucose and insulin values are taken at baseline (at the start of the study).
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
The Effects of the CF Carrier State on the Kidneys and Pancreas
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Philip M Polgreen, MD · PRINCIPAL_INVESTIGATOR · University of Iowa
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Comparison of Glucose ValuesAt baseline
Comparison of glucose values in cystic fibrosis carrier group vs control group via t-tests.
- Comparison of Insulin ValuesAt baseline
Comparison of insulin values in cystic fibrosis carrier group vs control group via t-tests.