This study is looking into how arginine (a nutrient) works in young people with Type 2 Diabetes (T2D). Researchers want to understand why T2D is increasing in youth and how arginine might help improve the function of beta-cells (cells in the pancreas that make insulin). You would receive a stable isotope infusion (a safe way to track substances in the body), drink a glucose solution, and get an intravenous (IV) arginine bolus (a quick injection of arginine) on separate study days. The main goal is to see how much arginine is available in your body after one day. This study is for youth aged 12 to 20 with T2D, and healthy controls, and is currently unclear regarding recruitment status.

Study design

This interventional study plans to enroll 30 participants. It aims to explore arginine metabolism and the effect of arginine administration on beta-cell function.

What's involved

On separate study days, participants will have a stable isotope infusion, ingest oral glucose, and receive an intravenous arginine bolus.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint measures arginine availability at 1 day.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.