Observational Study on Sleep in Childhood Cancer Survivors
This study aims to understand sleep patterns and sleep disorders in adults who survived childhood cancer, specifically those treated for acute lymphoblastic leukemia (ALL), central nervous system (CNS) tumors, or non-CNS solid tumors. Researchers will use various assessments like Neurocognitive (Thinking) Testing, CNS Vital Signs (Thinking) Testing, Health Questionnaires, Sleep Surveys & Sleep Diary, Echocardiography/EKG (heart tests), and Pulmonary Function (lung tests). The main goal is to find out how common different sleep disorders are in these groups. You can join if you are 18 or older, participated in SJLIFE, and are at least 5 years past your cancer diagnosis. This study is currently recruiting 199 participants.
- Study design
- This is an observational study planning to enroll 199 participants, with 40 in each of three groups. It is a cross-sectional pilot study, meaning it looks at a group of people at one point in time.
- What's involved
- You would complete various tests including thinking tests, heart and lung tests, and fill out health questionnaires, sleep surveys, and a sleep diary. Some activities may be done remotely or during campus visits.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
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Characterizing Sleep Among Long-term Survivors of Childhood Cancer
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Kevin Krull, PhD · PRINCIPAL_INVESTIGATOR · St. Jude Children's Research Hospital
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Insomnia Severity Index (ISI)Baseline
ISI is a seven-item questionnaire that looks at symptoms of clinical insomnia. The ISI assesses insomnia symptoms over the past 14 days and has demonstrated good reliability and validity. The total ISI score ranges from 0 to 28, with scores \< 8 indicating no significant insomnia.
- CSALTS Sleep SurveyBaseline
CSALTS Sleep Survey incorporating Epworth Sleepiness Scale (EPS) and Pittsburg Sleep Quality Index (PSQI) The CSALTS Sleep Survey assesses sleep quality, patterns, and daytime sleepiness. It incorporates 19 questions from the PSQI and 8 questions of the ESS. The PSQI and ESS total scores will be reported.
- Morningness-Eveningness Questionnaire (MEQ)Baseline
The MEQ is a 19-question measure that assesses the degree to which respondents are active and alert at certain times of the day. Each item is rated using a Likert-type scale with lower scales reflecting a more evening-type characterization of alertness. Global scores range from 16 to 86 and these values are used to define 'definitely morning type' (70-86), 'moderately morning type' (59-69), 'neither type' (42-58), 'moderately evening type' (31-41), and 'definitely evening type' (16-30).
- Circadian Type Inventory (CTI)Baseline
CTI is an 11-item questionnaire that looks at rigidity/flexibility of sleeping habits and ability/inability to overcome drowsiness (i.e., circadian rhythm disorders). Respondents use a 5-item, Likert-type scale to answer questions regarding their sleep habits and preferences. Scales range from 1 ("almost never") to 5 ("almost always"). Higher scores on the rigidity subscales indicate a greater flexibility in circadian rhythm, while lower scores on the overcoming-drowsiness subscale indicate a greater ability to manage on less sleep.
- Functional Assessment of Chronic Illness Therapy Fatigue Scale (FACIT)Baseline
fatigue scale is a short 13-item tool that provides a single measure of an individual's level of fatigue during a usual day.
- CSALTS Pain SurveyBaseline for 2 nights
The 7-item pain survey will include pain interference questions from the SJLIFE Behavioral Survey and one pain intensity question. The six items that measures amount of pain interference in daily activities in last 7 days is measured from "not at all" to "very much." The pain intensity question is measured 1-10 with 10 "worst imaginable pain."
- Polysomnography Evaluation (Sleep Profiler PSG2 or WatchPAT)Baseline
The Sleep Profiler PSG2 measures brain waves during sleep, blood oxygen levels, heart rate, and breathing and will measure different patterns of sleep stages. Two nights of data collection will be requested though one night will be sufficient if the participant sleeps at least 4 hours. The apnea hypopnea index and sleep efficiency scores will be reported. The WatchPAT device assesses sleep timing, sleep staging, and sleep apnea events via a device worn on the wrist that measures limb movement, peripheral arterial tone and connects to an EKG electrode. Two nights of data collection will be requested though one night will be sufficient if the participant sleeps at least 4 hours. The apnea hypopnea index and sleep efficiency scores will be reported