Access Cannulation Trial II for Dialysis Patients

This study is testing a device called VenaSure, which is surgically implanted at the access site for patients undergoing routine hemodialysis (a treatment that filters waste and water from your blood). The goal is to see if the VenaSure device helps make it easier to cannulate (insert needles into) arteriovenous fistulas (AVFs) for dialysis over the long term. Researchers will also be looking at how safe the device is. You might be able to join if you are 18 or older, and your AVF is difficult to cannulate because it's deeper than 6mm from your skin's surface. The study aims to enroll 100 participants and is currently unclear about its recruitment status.

Study design
This is a single-arm, open-label study, meaning all participants will receive the VenaSure device, and everyone will know what treatment is being given. It plans to include 100 participants.
What's involved
After the VenaSure device is implanted, you will be observed for 6 weeks as the site heals. You will then be monitored for 36 months during your routine dialysis treatments.
Compensation
Not stated in the trial record.
Follow-up
Participants will be monitored for 36 months after the device is implanted.

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NCT05490225

Access Cannulation Trial II

Recruiting
NAAges 18+InterventionalTreatment
Voyager Biomedical
~100 participants
Updated 2025-10-29 on ClinicalTrials.gov
What's tested:VenaSure

At a glance

Recruiting sites
8 of 8 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To demonstrate the effectiveness of the study device in facilitating cannulation of arteriovenous fistulas (AVFs) for hemodialysis.
Measured over 6 months
+1 more outcome measured
Dialysis; Complications
Vascular Access Complication
8 sites across 7 states
Texas2
Alabama1
California1
Massachusetts1
New York1
South Carolina1
Virginia1
  • Stephen Hohmann, MD · PRINCIPAL_INVESTIGATOR · Baylor Scott and White Health

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Arterial/Pull Zone: \_\_\_\_\_ x \_\_\_\_\_ mm in diameter
Venous/Push Zone: \_\_\_\_\_ x \_\_\_\_\_ mm in diameter 3. The subject has a flow rate of \<550mL/min in the inflow artery proximal to the arterial anastomosis as measured by ultrasound within 8 weeks prior to device implantation.
  • To demonstrate the effectiveness of the study device in facilitating cannulation of arteriovenous fistulas (AVFs) for hemodialysis.6 months

    Incidence of success for achieving clinically functional access within a 6-month timeframe from approved cannulation through the study device.

  • To evaluate the safety of the study device.12 months

    The assessment and occurrence of device-related, serious adverse events (SAEs) of clinical interest (infection, aneurysm, complicated seroma) during a 12- month follow-up period from initial implantation adjudicated by a Data Monitoring Committee (DMC)