Constraint-Induced Movement Therapy for Stroke Survivors with Mild Arm Weakness

This study is testing a treatment called Constraint-Induced Movement Therapy (CI Therapy) with added sensory components for adults who have had a stroke and still have some weakness in their arm. This therapy involves intensive training of the weaker arm, along with strategies to encourage its use in daily life. You might be able to join if you are at least 18 years old, had a stroke at least 6 months ago, and can move your wrist and fingers a certain amount. The researchers will measure how much and how well you use your affected arm to see if the treatment helps. The current status of this study is unclear, and it plans to enroll 12 participants.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 12 participants.
What's involved
Participants will receive Grade 1 CI Therapy + Sensory Components over a two-week period, with daily treatment sessions on consecutive weekdays.
Compensation
Not stated in the trial record.
Follow-up
Your arm function will be measured again at 3 months after the treatment ends.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05492513

Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment

Recruiting
NAAges 18+InterventionalTreatment
University of Alabama at Birmingham
~12 participants
Updated 2026-02-20 on ClinicalTrials.gov
What's tested:Grade 1 CI Therapy +Sensory Components

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
45-Item Motor Activity Log (MAL)
Measured over At post treatment after 2 weeks of intervention
+4 more outcomes measured
CVA (Cerebrovascular Accident)
Stroke
Upper Extremity Paresis

NCT05492513

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Alabama at Birmingham

    Birmingham, Alabamastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • David Morris, PhD · STUDY_CHAIR · University of Alabama at Birmingham

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Eligibility criteria

Inclusion

At least 6 months post stroke
The ability to demonstrate the minimum UE active movement criteria of 20 degrees of wrist extension from a fully flexed position, 10 degrees of thumb extension or abduction, and 10 degrees of extension of all finger joints.
Mean score of \>2.5 on the Motor Activity Log indicating the participant's use of the more-affected UE.

Exclusion

Score\< 24 on the Mini Mental State Exam
Inability to answer the MAL questions and/or provide informed consent
The inability to come in to the laboratory setting for treatment.
  • 45-Item Motor Activity Log (MAL)At post treatment after 2 weeks of intervention

    The 45-Item MAL is a semi-structured interview that assesses the amount of use and the quality of use of the more-affected UE in 45 activities of daily living. The use of this test is to determine the change how much and how well the participant uses the more-affected arm and hand outside of the laboratory setting. It is administered before and after treatment. The score is derived from a 0-5 scale and reported as a mean for the Amount of Use (AOU) and the Quality of Use (QOM).

  • 45-Item Motor Activity Log (MAL)At 3 months after the end of the treatment

    The 45-Item MAL is a semi-structured interview that assesses the amount of use and the quality of use of the more-affected UE in 45 activities of daily living. The use of this test is to determine the change how much and how well the participant uses the more-affected arm and hand outside of the laboratory setting. It is administered before and after treatment. The score is derived from a 0-5 scale and reported as a mean for the Amount of Use (AOU) and the Quality of Use (QOM).

  • Wolf Motor Function Test (WMFT)At post treatment after the 2 weeks of intervention

    The WMFT is a standardized test that measures the motor ability of the upper extremities of a participant. The performance time by stopwatch is recorded and functional ability (quality) score is provided for each item tested. It is administered before treatment and after treatment. The quality of movement is rated by the therapist on a scale from 0-5 with 0 representing the participant's inability to perform the task, and 5 representing normal movement or as good as before the stroke, such that a higher functional ability score is better. A lower performance represents a better performance.

  • Canadian Occupational Performance Measure (COPM)At post-treatment after the 2 weeks of intervention

    The COPM is a semi structured interview in which the participant is asked to rate desired occupational performance areas for activities of daily living and instrumental activities of daily living. The COPM is used to show changes in performance and satisfaction in desired areas of occupational performance. There are three scales used in the COPM administration one for importance, performance, and satisfaction. The scales range from 1-10 with the higher score indicating an improvement in the score.

  • Canadian Occupational Performance Measure (COPM)At follow-up at 3 months following the end of treatment.

    The COPM is a semi structured interview in which the participant is asked to rate desired occupational performance areas for activities of daily living and instrumental activities of daily living. The COPM is used to show changes in performance and satisfaction in desired areas of occupational performance. There are three scales used in the COPM administration one for importance, performance, and satisfaction. The scales range from 1-10 with the higher score indicating an improvement in the score.