Caloric Restriction and Glucagon in Type 2 Diabetes
This study is looking at how a special diet, called caloric restriction, affects how the body uses sugar and fats in people with Type 2 Diabetes. Researchers want to see if eating 900 calories a day, using meals from "Nutritional Guidelines after Bariatric Surgery," can improve how the body responds to glucagon (a hormone that raises blood sugar). You might be able to join if you are 25-65 years old, have Type 2 Diabetes managed by diet or oral medications, and a BMI of 28 or higher. The main goal is to measure how a specific amino acid (leucine) is used when glucagon levels change. The study is currently unclear on its status and plans to enroll 20 participants.
- Study design
- This is an interventional study with 20 planned participants. The phase of the study is not specified.
- What's involved
- You would follow a 900-calorie daily diet, with weekly meetings with a dietician. You would also undergo a hyperglycemic clamp procedure to measure glucagon's effects.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint is measured at 240 minutes of study, which gives an indication of the measurement period.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
The Effects of Glucagon on Hepatic Metabolism in People With Type 2 Diabetes After Caloric Restriction
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Adrian Vella · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Rate of leucine oxidation in response to rising glucagon concentrations240 minutes of study
tracer-determined amino acid catabolism