Sex Selection of Human Spermatozoa Study

This study is looking for couples undergoing infertility treatment (IVF or insemination) who want to choose the gender of their child for medical or non-medical reasons. It aims to find a simple, reliable, and affordable way to select sperm that will result in a boy or a girl. Researchers will use a special procedure called Sperm Sorting, which involves a multilayer density gradient solution (Enhance-S Plus Cell Isolation Media) to separate sperm. This selected sperm will then be used in standard IVF or intrauterine insemination procedures. The study will measure how well this method works by looking at the percentage of desired gender sperm after sorting, and later, the gender of embryos and offspring. The study is currently unclear on its recruitment status and plans to enroll 2000 participants aged 18 to 89 years.

Study design
This interventional study aims to enroll 2000 participants to test a method for selecting gender-specific sperm.
What's involved
Couples will undergo evaluation and treatment following standard clinic procedures, and males will provide sperm samples for analysis and sorting.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 8 years to assess the gender of embryos and offspring.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05500573

Sex Selection of Human Spermatozoa

Recruiting
NAAges 18–89InterventionalTreatment
Weill Medical College of Cornell University
~2,000 participants
Updated 2026-05-29 on ClinicalTrials.gov
What's tested:Sperm Sorting

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Rate of gender bearing spermatozoa after 4-layer density gradient
Measured over 8 years
+2 more outcomes measured
Infertility
IVF
1 sites across 1 states
New York1
  • Gianpiero Palermo, MD, PhD · PRINCIPAL_INVESTIGATOR · Weill Medical College of Cornell University

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Couples undergoing infertility treatment with IVF or insemination seeking gender specific offspring for medical and non medical reasons

Exclusion

Severe male factor
  • Rate of gender bearing spermatozoa after 4-layer density gradient8 years
  • Rate of embryos of the desired gender in couples8 years
  • Rate of offspring of the desired gender in couples8 years